Here are the next seven mysteries on the list:

What’s up with prime numbers?
How do we beat bacteria?
Can computers keep getting faster?
Will we ever cure cancer?
When can I talk to my robot?
What’s at the bottom of the ocean?
What’s at the bottom of a black hole?

It is likely that some or all of these will remain unsolved for a very long time.  Do you have any thoughts or theories in regards to these?  Feel free to comment!